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- США
- Зарплата
- 160 000 $ – 180 000 $
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Senior Lab Automation Engineer
Отличное предложение в быстрорастущем секторе биотеха с конкурентной зарплатой, бонусами и опционами. Четко прописанные обязанности и работа с передовыми технологиями делают вакансию очень привлекательной для опытных инженеров.
Сложность вакансии
Роль требует глубоких знаний в узкой нише: программирование жидкостных роботов (Hamilton), интеграция сложного оборудования и понимание биохимических процессов. Высокая ответственность за полный жизненный цикл систем в регулируемой среде (ISO 13485/FDA) повышает порог входа.
Анализ зарплаты
Предложенная зарплата ($160k - $180k) находится на верхней границе рыночного диапазона для Senior-позиций в области автоматизации лабораторий в районе залива Сан-Франциско, что отражает высокую ценность узкой специализации.
Сопроводительное письмо
I am writing to express my strong interest in the Senior Lab Automation Engineer position at Alamar Biosciences. With extensive experience in developing and optimizing automated workflows on liquid handling platforms, particularly Hamilton STAR systems, I am confident in my ability to contribute to your next-generation proteomics platform. My background in bridging the gap between complex assay chemistry and robust robotic integration aligns perfectly with Alamar's mission to enable ultra-sensitive disease detection.
Throughout my career, I have demonstrated a commitment to building scalable and maintainable solutions, moving beyond simple fixes to root-cause analysis and system-level optimization. I am particularly drawn to Alamar's collaborative culture and the challenge of translating intricate assay requirements into high-throughput, reliable automation protocols. I look forward to the possibility of bringing my technical expertise in Hamilton Venus/HSL and Python, along with my experience in regulated biotech environments, to your innovative team.
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Описание вакансии
At Alamar, we are passionate about enabling our customers to make scientific discoveries that translate into clinical outcomes and benefit patients. Our team is growing quickly as we develop innovative approaches to measure critical protein biomarkers from liquid samples that can enable the earliest possible detection of disease. We believe the next frontier in biology is enabled by measuring proteins at higher sensitivity in highly multiplexed assays at the push of a button, which is something only Alamar can do. As we build our team, we seek collaborative, driven, intellectually curious people committed to solving complex challenges. Our culture rewards accountability and cross functional teamwork because we believe this enables the kind of breakthrough thinking that will accelerate our mission.
At Alamar Biosciences, we are building a next-generation proteomics platform to enable ultra-sensitive detection of disease at its earliest stages. Our fully automated, high-throughput systems integrate complex assay chemistry, robotics, and data workflows to unlock new frontiers in biomarker discovery and diagnostics.
We are seeking a Senior Lab Automation Engineer who thrives in hands-on environments, takes ownership of complex systems, and can bridge biology, engineering, and software. This role is central to developing, scaling, and sustaining automated workflows across both R&D and production environments.
What You’ll Do
- Own automation systems end-to-end: from concept and requirements through integration, validation, deployment, and lifecycle support
- Design, develop, and optimize automated workflows on liquid handling platforms (e.g., Hamilton, Tecan, Opentrons) and integrated instrument systems
- Translate assay requirements into robust, scalable automation protocols with high reliability and throughput
- Drive debugging and root-cause analysis across hardware, software, and assay interactions—not just symptom-level fixes
- Integrate automation platforms with peripheral devices (thermal cyclers, shakers, readers, storage systems, robotics, etc.)
- Develop and maintain automation code (e.g., Hamilton Venus/HSL, Python, or similar) with an emphasis on modularity, maintainability, and traceability
- Lead or contribute to verification & validation (V&V) activities, including protocol qualification, performance characterization, and failure analysis
- Partner cross-functionally with assay development, mechanical/electrical engineering, manufacturing, and software teams to deliver cohesive system solutions
- Improve system performance through process optimization, error reduction, and throughput scaling
- Create clear, audit-ready documentation (SOPs, work instructions, validation protocols, troubleshooting guides)
What We’re Looking For
Core Requirements
- MS (or higher) in Engineering (Mechanical, Electrical, Chemical, Bioengineering, or related) with 5+ years of relevant experience, or equivalent practical experience
- Strong hands-on experience with liquid handling automation platforms (Hamilton STAR preferred; Tecan, Opentrons, or similar also relevant)
- Deep experience in automation programming (e.g., Hamilton Venus/HSL, Python, C#, or equivalent)
- Proven ability to debug complex systems spanning fluidics, robotics, software, and assay chemistry
- Experience developing or supporting high-throughput automated workflows in biotech or diagnostics settings
- Strong technical documentation skills (experimental design, data analysis, SOPs, validation documentation)
Preferred / High-Value Experience
- Experience integrating multi-instrument systems (robotics, readers, thermal modules, storage systems)
- Familiarity with design controls, V&V, and regulated environments (e.g., CLIA, CAP, ISO 13485, or FDA)
- Experience with assay automation (NGS, PCR/qPCR, proteomics, or similar)
- Exposure to data pipelines, LIMS, or instrument software integration
- Experience scaling workflows from R&D to manufacturing or clinical environments
What Sets You Apart
- You don’t stop at “it works”—you push for robust, scalable, and maintainable solutions
- You are hands-on and pragmatic, but capable of thinking at the system architecture level
- You proactively identify gaps, failure modes, and inefficiencies—and fix them at the root
- You learn fast, adapt quickly, and take ownership without waiting for direction
- You can operate effectively in ambiguous, fast-moving environments
Work Environment
- This is a lab-intensive, hands-on role involving frequent interaction with instruments and experimental workflows
- You will work closely with a multi-disciplinary team across engineering, assay development, and operations
The base salary range for this full-time position is $160,000 - $180,000 + bonus + equity + benefits. Our salary ranges are determined by work location, job-related skills, experience, and relevant education or training. The ranges displayed on each job posting reflect the minimum and maximum target for new hire salaries but are subject to change if the leveling of the role is adjusted. Your recruiter can share more about the specific salary range during the hiring process.
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Навыки
- C++
- Python
- Robotics
- ISO 13485
- LIMS
- Liquid Handling
- Hamilton VENUS
- HSL
- Assay Automation
- Validation & Verification
Возможные вопросы на собеседовании
Проверка практического опыта работы с ключевым оборудованием, указанным в вакансии.
Опишите ваш опыт программирования на Hamilton Venus/HSL. С какими наиболее сложными ошибками в логике распределения жидкостей вы сталкивались?
Оценка способности кандидата работать на стыке инженерии и биологии.
Как вы подходите к переводу ручного протокола анализа (assay) в полностью автоматизированный процесс, обеспечивая при этом воспроизводимость результатов?
Важно понять, как кандидат справляется с системными сбоями.
Расскажите о случае, когда вам пришлось проводить глубокий поиск первопричины (root-cause analysis) в системе, где взаимодействуют механика, ПО и химия.
Проверка навыков системной интеграции.
Какой у вас опыт интеграции сторонних устройств (термоциклеров, ридеров) в единый автоматизированный воркфлоу? Какие протоколы связи вы использовали?
Оценка готовности к работе в условиях жестких стандартов качества.
Какую роль вы играли в процессах верификации и валидации (V&V) автоматизированных систем в вашей предыдущей практике?
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- Страна
- США
- Зарплата
- 160 000 $ – 180 000 $