Process Development TIL therapy Intern

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Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer.

Overview

Our ideal candidate will be a highly talented and motivated individual who wants to further their understanding of Tumor-infiltrating lymphocyte (TIL) therapy biology and thrive doing bench work. The intern will work with our Process Development (PD) Scientist team to evaluate TIL expansion in the full-scale manufacturing process and evaluate the cell density impact on TIL growth. The work will involve observing and generating transducing TIL and characterization through different ex-vivo assays and culture methods. The intern will have the opportunity to gain hands-on experience in the biotech industry, including working with cutting-edge equipment and technologies. At the end of the internship, the intern will be expected to present a summary of the work they completed during their training period.

Essential Functions and Responsibilities

• Must be able to work up to 40 hours a week for 12 weeks.
• Observe and perform PD experiments under the guidance of a PD Scientist.
• Participate in analyzing and interpreting data.
• Generate graphs and present results during group meetings.
• Able to follow established protocols and work in a fast-paced environment.
• Good communication skills.
• Able to work in a highly collaborative environment.
• Able to work in a BSL-2 lab setting and handle lentivirus.
• Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics.
• Comply with Safety SOPs, SDS sheets, and laboratory procedures per company policy and OSHA regulations.
• Perform all other related duties as assigned.

Required Education, Skills, and Knowledge

• Must be enrolled in a university program pursuing a Bachelor’s in Immunology, Biological Sciences, Cancer Biology, or Cell & Molecular Biology Or related life science field.
• Proficient with computers and Microsoft Office Suite (PowerPoint, Excel, Word).
• Self-motivated, enthusiastic, and results-oriented.
• Must be able to communicate (verbal and written) effectively.
• Must be organized, be able to multitask, and be a team player.

Preferred Education, Skills, and Knowledge

• Bachelor or master’s Students in Immunology, Molecular Biological Sciences, Cancer Biology, or related fields are also encouraged to apply.
• Experience in scientific research.
• Human primary cell/tissue handling.
• Experience in biology and process development or GMP manufacturing.

Physical Demands and Activities Required

• Must be able to move to and from the office to the lab located on separate floors and move about the office and lab as needed.
• Must be able to remain in a stationary position standing or sitting for prolonged periods of time.
• Must be able to move and lift up to 20 pounds multiple times a day.
• Wear proper personal protective equipment in a laboratory setting, i.e., safety glasses, lab coats, and closed-toed shoes.

Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines.

Work Environment

This position will work in an office and a laboratory setting, routinely using standard office equipment such as computers, copiers, printers, and filing cabinets. When in the lab, there may be a risk of exposure to hazardous or biological waste within the environment through receipt, transport, storage, preparation, dispensing, administration, cleaning, and/or disposal of contaminated areas and waste.

The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time.

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The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time.

Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com.

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