- Страна
- США
- Зарплата
- 117 400 $ – 146 800 $
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Senior Bioinformatics Scientist (Oncology Product Development)
Natera — признанный лидер в своей области с отличным социальным пакетом и возможностью удаленной работы. Позиция предлагает участие в создании продуктов, спасающих жизни, что обеспечивает высокую профессиональную значимость.
Сложность вакансии
Высокая сложность обусловлена требованием ученой степени (PhD/Master's) и глубоких знаний в узких областях, таких как метилирование ДНК и статистическое моделирование для онкологии. Работа предполагает полный цикл разработки продукта в высококонкурентной среде биотехнологий.
Анализ зарплаты
Предлагаемый диапазон $117k–$146k находится в пределах рыночной нормы для Senior-позиций в биоинформатике в США, однако верхняя граница может быть несколько ниже, чем в крупнейших технологических хабах (например, Бостон или Сан-Франциско), где медиана может достигать $160k+. Тем не менее, для удаленной роли это конкурентоспособное предложение.
Сопроводительное письмо
I am writing to express my strong interest in the Senior Bioinformatics Scientist position at Natera. With a solid background in quantitative analysis and extensive experience in developing bioinformatics pipelines for NGS data, I am eager to contribute to your Oncology Product Development team. My expertise in Python-based scientific computing and statistical modeling aligns perfectly with Natera's mission to advance ctDNA-based diagnostic tests.
Throughout my career, I have focused on transforming complex genetic data into actionable clinical insights. I am particularly drawn to this role because of Natera's leadership in cell-free DNA testing and the opportunity to work on DNA methylation patterns. I am confident that my experience in building production-grade algorithms and my commitment to rigorous data analysis will help drive the next generation of oncology products from research to commercial launch.
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Откликнитесь в natera уже сейчас
Присоединяйтесь к лидеру в области генетического тестирования и внесите свой вклад в борьбу с раком — подайте заявку на позицию Senior Bioinformatics Scientist сегодня!
Описание вакансии
Natera is currently seeking a Senior Bioinformatics Scientist to join the Bioinformatics team focused on Oncology Product Development. The individual will participate in the design and prototyping of cutting-edge algorithms for analysis of genetic data and the development and validation of ctDNA-based diagnostic tests, interacting closely with colleagues in our molecular biology and biostatistics teams to guide and analyze experiments. The ideal candidate will have a strong background in bioinformatics and data science, optimally with experience in the analysis or modeling of DNA methylation data.
PRIMARY RESPONSIBILITIES:
- Develop and improve analysis pipelines for diagnostic tests, including detection of cancer-associated variants or methylation patterns and implementation of evidence-based quality control thresholds.
- Leverage accurate statistical or probabilistic models to build the next round of algorithms and products.
- Move products through the full development process, from research through commercial launch.
- Help design and interpret molecular biology experiments.
- Contribute to our intellectual property portfolio.
- Drive rigorous data analysis efforts and support group efforts in the production of high-quality documentation.
QUALIFICATIONS:
Requirements:
- Master’s degree or Ph.D. in a quantitative discipline (bioinformatics, engineering, applied mathematics, statistics, or similar).
- Minimum of 2-3 years of post-graduate experience in a data science and/or bioinformatics role.
Desirable, but not required:
- Prior experience analyzing or modeling DNA methylation data.
KNOWLEDGE, SKILLS, AND ABILITIES:
- Experience using Python for scientific data analysis and visualization.
- Strong foundation in statistical modeling/machine learning, including probability theory and estimation/classification methods.
- Experience with analysis of next-generation sequencing data, preferably including algorithm development or optimization.
- Proven ability to apply mathematical principles to solve real estimation problems and implement practical solutions.
- Experience writing code in a production environment and using version control.
- Excellent communication skills and the desire to work in a dynamic and collaborative environment.
The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$117,400—$146,800 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
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Навыки
- Python
- Bioinformatics
- Next Generation Sequencing
- Statistical Modeling
- Machine Learning
- Data Science
- DNA Methylation
- Version Control
- Algorithms
- Oncology
Возможные вопросы на собеседовании
Проверка опыта работы с ключевой технологией, упомянутой в вакансии.
Опишите ваш опыт анализа данных метилирования ДНК и какие специфические статистические модели вы использовали для этого?
Оценка навыков разработки алгоритмов для клинических тестов.
Как бы вы подошли к установлению порогов контроля качества (QC) для нового диагностического теста на основе ctDNA?
Проверка инженерных навыков в контексте биоинформатики.
Расскажите о вашем опыте написания кода для производственной среды. Как вы обеспечиваете воспроизводимость и масштабируемость ваших пайплайнов?
Оценка способности работать на стыке дисциплин.
Приведите пример, когда результаты вашего биоинформатического анализа напрямую повлияли на дизайн молеклярно-биологического эксперимента.
Проверка фундаментальных знаний статистики.
Какие методы классификации вы считаете наиболее эффективными для обнаружения редких вариантов в данных NGS и почему?
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- Страна
- США
- Зарплата
- 117 400 $ – 146 800 $